Geopolitical trends can create new enemies, reintroduce old ones, and likewise cause tension over issues new and old. The effect of geopolitics on cybersecurity make the headlines each day—from Russian attacks on Ukraine, Chinese cyber espionage, Iranian attacks on oil tanks in the Persian Gulf to North Korea’s financially motivated attacks against SWIFT and Bitcoin. While non-state cybercriminals predominately chase after new opportunities for profit that arise in this shifting environment, nation state-sponsored threat actors more often seek political motives beyond money. This presentation will focus on nation state actors and discuss how China and Iran have used cyber operations to support their national interests in response to geopolitical tensions. Furthermore, this presentation will discuss security implications for US businesses and government organizations as China and Iran continue to improve their capabilities for computer network operations in this current shifting geopolitical environment. Lastly, this presentation will touch on strategies to build cyber resilience against nation state-sponsored threats.